JUNIOR PI (M/F) PEPR Cell-ID - UMR3664
About us Institut Curie Research Center Institut Curie, France's leading cancer center, comprises a state-of-the-art hospital specialized in cancer treatment and an internationally renowned multidisciplinary research center combining research in cell biology, genetics, epigenetics, immunology, soft matter physics, organic chemistry, and medicinal chemistry. It brings together more than 3,800 researchers, doctors, clinicians, technicians, and administrative staff across three sites: Paris, Orsay, and Saint-Cloud. The institute's facilities include an advanced imaging platform with a wide variety of high-end microscopes, from confocal to super-resolution imaging, imaging of living cells and small animals. Other facilities include single-cell technologies, small molecule and CRISPR screening, high-throughput sequencing, bioinformatics, proteomics and mass spectrometry, antibody technologies and protein purification, nano-SIMS, cytometry, and animal housing. In addition, the proximity to the hospital allows to access to large clinical databases and sample collections and an exceptional environment for pediatric oncology research. Mission The PEPR Cell-ID ( Programmes et Équipements Prioritaires de Recherche Identités et Destins Cellulaires ) is recruiting a junior team leader to develop innovative computational approaches for studying cellular destiny and nuclear organization. The team will be part of UMR3664 “Nuclear Dynamics” led by Dr. Angela Taddei at Institut Curie (75005). The PEPR Cell-ID, under the scientific direction of Dr. Geneviève Almouzni, is funded by France 2030 and co-led by the CNRS and Inserm. Its objective is to deploy experimental technologies and cutting-edge analysis methods for cell-based interception medicine, particularly in the context of pediatric brain cancers. Comprising 31 research teams in France, including 11 at the Institut Curie, it has a budget of €50 millions over seven years. UMR3664, located within the Institut Curie research center in Paris's 5th arrondissement, is composed of seven teams studying the links between genetic and epigenetic information during development and during the establishment of the diversity of cellular destinies and identities that compose an entire organism. This unit maintains close interactions with units such as the U1330 “Mechanisms of Oncogenesis in Pediatric Tumors” led by Dr. Olivier Ayrault, U1331 “Computational Oncology” led by Dr. Emmanuel Barillot, UMR3215/U934 “Genetics and Developmental Biology” led by Dr. Yohanns Bellaiche, UMR144 “Cell Biology and Cancer” led by Dr. Franck Perez, UMR168 “Cell Physics and Cancer” led by Dr. Pascal Hersen, and the MIT with Dr. Leonid Mirny. The competitive funding provided by the PEPR Cell-ID program and its network will enable the successful candidate to develop, within the collaborative context of the PEPR, innovative approaches to data analysis, integration, visualization, and modelling using new technologies at the individual cell level in order to better characterize the regulation of cell fate during development in physiological or pathological contexts. Candidates will be selected based on the quality of their scientific record and how their future research project will be integrated within the Cell-ID and UMR3664 research scope. Their involvement in training, awareness-raising, or outreach activities will be considered an asset. The team leader recruited will benefit from the expertise of the PEPR and Institut Curie teams through an exceptional research environment at the local and national level and state-of-the-art equipments available in the unit, within the Institute's and PEPR's technology platforms. At the outset, office space for six peoples and financial support will be allocated. The successful candidate will meet the eligibility criteria to apply for French institutional research positions (CNRS, INSERM, or University) and national and international funding. Profile Education and knowledge
- Education: Ph.D. in biology, physics, or a related quantitative discipline, with significant experience in computational biology or quantitative modelling of biological systems
- Skills acquired during education or previous experiences: Successful postdoctoral experience(s) with publications in peer-reviewed journals in the field.
- Language skills: English
- Autonomy, managerial and organizational skills, ability to work collaboratively
- Writing and communication skills
- Awareness of societal, equity, inclusion, and diversity issues
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